Stromal cell-derived factor-1α regulates chondrogenic differentiation via activation of the Wnt/β-catenin pathway in mesenchymal stem cells

Figure 5 Effects of stromal cell-derived factor-1α on the cartilage phenotype of primary rat chondrocytes. A: Expression levels of collagen II, aggrecan, collagen X, and matrix metalloproteinase 13 (MMP13) were determined by western blotting in primary chondrocytes treated with stromal cell-derived factor-1α (100 ng/mL); B: Relative collagen II, aggrecan, collagen X, and MMP13 protein expression. ^aP < 0.05 vs control (Student’s t-test), ^bP < 0.01 vs control (Student’s t-test). MMP13: Matrix metalloproteinase 13; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; sdf-1α: Stromal cell-derived factor-1α.