Repetitive administration of cultured human CD34+ cells improve adenine-induced kidney injury in mice

Figure 4 Histological analysis of renal injury. A and B: Tubular injury including tubular dilatation, tubular epithelial atrophy, and tubular atrophy, evaluated using periodic acid-Schiff-stained renal tissue sections of control group (A) and cell therapy group (B); C and D: Interstitial fibrosis using Masson’s trichrome stained sections of control group (C) and cell therapy group (D). Scale bar: 200 μm; E: Quantitative analysis of interstitial fibrosis rate, and F: semi-quantitative analysis of tubular injury score. Statistical significance of Figure 4E and F were determined using Mann-Whitney U test.