Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts

Figure 7 MiR-144-3p and miR-23b-3p regulate the proliferation, migration and collagen synthesis of NIH3T3 fibroblasts. A: Bromodeoxyuridine assay was performed to measure the proliferation ability; B: Wound healing assay was performed to measure the migratory capability; C: Immunofluorescence was performed to determine the effects of miR-144-3p and miR-23b-3p on COL I and α-smooth muscle actin expression. n = 3 per groups. Data are shown as mean ± SD. ^aP < 0.05, ^bP < 0.01. α-SMA: α-smooth muscle actin.