Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts

doi:10.4252/wjsc.v15.i4.248

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Apr 26, 2023 (publication date) through Jan 23, 2025

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Apr 26, 2023; 15(4): 248-267
Published online Apr 26, 2023. doi: 10.4252/wjsc.v15.i4.248

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Figure 5 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis of hub-gene targets. A: Top 10 hub-gene targets for hsa-miR-144-3p; B: Top 10 hub-gene targets for hsa-miR-23b-3p; C-E: Top 10 Gene Ontology biological process, cellular component, and molecular function terms enriched in the top 20 hub-gene targets; F: Top 10 Kyoto Encyclopedia of Genes and Genomes pathways enriched in the 20 hub-gene targets; G: Interaction network of the two microRNAs and their hub-gene targets.

Citation: Li FQ, Chen WB, Luo ZW, Chen YS, Sun YY, Su XP, Sun JM, Chen SY. Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts. World J Stem Cells 2023; 15(4): 248-267
URL: https://www.wjgnet.com/1948-0210/full/v15/i4/248.htm
DOI: https://dx.doi.org/10.4252/wjsc.v15.i4.248