Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells

Figure 4 TdT-mediated dUTP nick-end labeling and histopathology analysis of kidney tissues from all rats. A: TdT-mediated dUTP nick-end labeling staining. Nuclei: Blue; apoptosis: Green; B: Hematoxylin-eosin staining; C: Periodic acid-Schiff (PAS) staining; D: Mesangial index of PAS-positive areas in the glomerulus; E: Immunohistochemical staining of advanced glycation end products (AGEs); F: Integrated optical density of AGEs in kidney tissues. All scale bar: 50 μm. Data are presented as the mean ± SD. ^aP < 0.001 vs normal control group, ^bP < 0.001 vs normal control group, ^cP < 0.05 vs diabetic kidney disease group. AGEs: Advanced glycation end products; NC: Normal control; DKD: Diabetic kidney disease; MSCs: Mesenchymal stem cells.