Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model

Figure 10  Cell tracking analysis. A: Fluorescence images showing DiI labeled mesenchymal stem cells (MSCs) in the scaffold near the border of the scaffold and the infarcted myocardium, and co-localized green fluorescent cardiac proteins, cardiac myosin heavy chain, cardiac troponin T, and cardiac troponin I in the untreated and zebularine treated MSC-seeded scaffold transplanted rat heart; B: Quantification of fluorescence intensities showing significantly higher intensity of DiI labeled MSCs and protein expression in zebularine treated MSC-seeded scaffold group. Data is presented as mean ± standard error of mean with significance level ^aP < 0.05 (where ^aP < 0.05). MSC: Mesenchymal stem cells; DAPI: 4',6-diamidino-2-phenylindole. cTnT: Cardiac troponin T; cTnI: Cardiac troponin I; cMHC: Cardiac myosin heavy chain; DAPI: 4',6-diamidino-2-phenylindole.