Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model

Figure 4 Gene expression analysis of cardiac markers. Bar graphs representing fold change of cardiac specific genes, GATA4, cardiac troponin T (cTnT), cardiac troponin I (cTnI), Nkx2.5, cardiac myosin heavy chain (cMHC), connexin43, atrial natriuretic factor (ANF), T-box transcription factor 20 (Tbx20), and myocyte-specific enhancer-binding factor 2C (Mef2C) in different types of zebularine treated mesenchymal stem cell-seeded scaffolds compared to untreated control. A: GATA4; B: cTnT; C: cTnI; D: Nkx2.5; E: cMHC; F: Connexin43; G: ANF; H: Tbx20; I: Mef2C. GATA4, cTnT, connexin43, ANF, Tbx20, and cMHC showed significant increase in type 3 treatment as compared to control and other groups. Data is presented as mean ± standard error of mean with significance level ^aP < 0.05 (where ^aP < 0.05, ^bP < 0.01, ^cP < 0.001).