Metabolic determinants of stemness in medulloblastoma

doi:10.4252/wjsc.v14.i8.587

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Aug 26, 2022 (publication date) through Dec 27, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Aug 26, 2022; 14(8): 587-598
Published online Aug 26, 2022. doi: 10.4252/wjsc.v14.i8.587

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Figure 2 Metabolic pathways upregulated in medulloblastoma. Enzymes from glycolysis or fatty acid synthesis pathways upregulated in medulloblastoma (MB) tumours are highlighted in different colours indicating the MB subgroup (Sonic hedgehog [SHH]: Grey, WNT: Yellow, Group 3: Green, Group 4: Blue). Statistically significant prognostic genes are marked with the asterisk (*). GLUT4: Glucose transporter type 4; HK2: Hexokinase 2; PKM2: Pyruvate kinase M2; LDHA: Lactate dehydrogenase A; ACLY: ATP citrate lyase; FASN: Fatty acid synthase; SCD: Stearoyl-CoA desaturase; SHH: Sonic hedgehog.

Citation: Martín-Rubio P, Espiau-Romera P, Royo-García A, Caja L, Sancho P. Metabolic determinants of stemness in medulloblastoma. World J Stem Cells 2022; 14(8): 587-598
URL: https://www.wjgnet.com/1948-0210/full/v14/i8/587.htm
DOI: https://dx.doi.org/10.4252/wjsc.v14.i8.587