Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model

Table 3 Echocardiographic parameters

Groups	Duration	LVIDd (cm)	LVIDs (cm)	EF%	FS%	EDV (mL)	ESV (mL)	SV (mL)
Sham control	2 wk	0.4194	0.1639	93.5889	60.9556	0.0722	0	0.0667
MI + ve		0.5156	0.3722	62.5556	28.3056	0.1389	0.05	0.1056
MI + scaffold		0.5193	0.332	74.4467	37.3067	0.1533	0.04	0.1133
MI + MSC-seeded scaffold		0.4461	0.2611	78.8	40.9389	0.1167	0	0.0667
MI + zebularine treated MSC-seeded scaffold		0.5144	0.2972	80.2111	42.1278	0.1444	0	0.1278
Sham control	4 wk	0.4705	0.195	92.7389	59.2222	0.1222	0	0.1111
MI + ve		0.5780	0.4363	57.3306	24.9194	0.1889	0.0833	0.1222
MI + scaffold		0.47	0.305	73.1056	36.3278	0.1222	0.0333	0.0833
MI + MSC-seeded scaffold		0.5772	0.3455	78.0056	40.5667	0.2111	0.0389	0.1667
MI + zebularine treated MSC-seeded scaffold		0.5338	0.285	82.6056	45.6611	0.1667	0	0.1222
Sham control	6 wk	0.5183	0.2333	90.3333	54.8667	0.15	0	0.1333
MI + ve		0.7066	0.5716	46.85	19.55	0.3444	0.2	0.1611
MI + scaffold		0.5472	0.3622	70.0444	33.8889	0.1667	0.0389	0.1278
MI + MSC-seeded scaffold		0.5533	0.3288	78.05	40.8611	0.1722	0.0333	0.1444
MI + zebularine treated MSC-seeded scaffold		0.5589	0.3156	81.7028	43.7972	0.17778	0.0167	0.1528

LVIDd: Left ventricular internal diameter diastole; LVIDs: Left ventricular internal diameter systole; EF: Ejection fraction; FS: Fractional shortening; EDV: End diastolic volume; ESV: End systolic volume; SV: Stroke volume; MI: Myocardial infarction; MSC: Mesenchymal stem cells.