Optimization of adipose tissue-derived mesenchymal stromal cells transplantation for bone marrow repopulation following irradiation

Figure 3 Characterization of red blood cell parameters in peripheral blood and CD34⁺ hematopoietic stem cells in the bone marrow. A-C: Hematocrit level, hemoglobin level, and red blood cells count in the control, irradiated (RT), and stem cell-treated (ST)#1 groups at three weeks post-whole-body irradiation (WBI); D-F: Mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and mean corpuscular volume for the control, RT, and ST#1 groups at three weeks post-WBI; G-M: Immunohistochemistry for CD34⁺ hematopoietic cells (green) in bone marrow; nuclei were counterstained with 4’,6-diamidino-2-phenylindole (blue). Magnification 400 ×; scale bar 50 μm; ^aP < 0.01 vs controls. RBC: Red blood cell; MCH: Mean corpuscular hemoglobin; MCHC: Mean corpuscular hemoglobin concentration; MCV: Mean corpuscular volume; NC: Normal control; ST: Stem cell-treated; RT: Irradiated.