Copyright
©The Author(s) 2022.
World J Stem Cells. Dec 26, 2022; 14(12): 822-838
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.822
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.822
Figure 8 SPOC domain-containing protein 1 expression in the testes of obstructive azoospermia and non-obstructive azoospermia patients.
A and B: Proportions of glial cell line-derived neurotrophic factor family receptor alpha-1-positive spermatogonial stem cells (red) with SPOC domain-containing protein 1 (SPOCD1) expression (green) in obstructive azoospermia (OA) with normal spermatogenesis and other types of non-obstructive azoospermia (NOA) patients; C and D: Western blot analysis shows SPOCD1 protein levels in OA and NOA patients. In (A), each picture represents one testicular sample. Each group had two samples. HS: Hypospermatogenesis; Normal: Normal spermatogenesis; Spc MA: Spermatocyte maturation arrest; Spg MA: Spermatogonia maturation arrest. Scale bar in A: 50 μm. aP < 0.05.
- Citation: Zhou D, Zhu F, Huang ZH, Zhang H, Fan LQ, Fan JY. SPOC domain-containing protein 1 regulates the proliferation and apoptosis of human spermatogonial stem cells through adenylate kinase 4. World J Stem Cells 2022; 14(12): 822-838
- URL: https://www.wjgnet.com/1948-0210/full/v14/i12/822.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v14.i12.822