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©The Author(s) 2022.
World J Stem Cells. Dec 26, 2022; 14(12): 822-838
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.822
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.822
Figure 5 Effects of SPOC domain-containing protein 1 inhibition on apoptosis of human spermatogonial stem cells.
A and B: Flow cytometry and APC Annexin V analysis show proportions of early and late apoptotic cells in human spermatogonial stem cells (SSCs) transfected with negative control (NC)-small interfering RNA (siRNA) and SPOC domain-containing protein 1-siRNA 2; C and D: Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) analysis shows proportions of TUNEL-positive cells in human SSCs transfected with NC-siRNA and forkhead box P4 (FOXP4)-siRNA 2. Scale bars in C: 20 μm. aP < 0.05.
- Citation: Zhou D, Zhu F, Huang ZH, Zhang H, Fan LQ, Fan JY. SPOC domain-containing protein 1 regulates the proliferation and apoptosis of human spermatogonial stem cells through adenylate kinase 4. World J Stem Cells 2022; 14(12): 822-838
- URL: https://www.wjgnet.com/1948-0210/full/v14/i12/822.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v14.i12.822