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©The Author(s) 2022.
World J Stem Cells. Dec 26, 2022; 14(12): 822-838
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.822
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.822
Figure 3 Expression pattern of SPOC domain-containing protein 1 in normal adult testis.
A: Western blotting show SPOC domain-containing protein 1 (SPOCD1) levels in three obstructive azoospermia (OA) samples with normal spermatogenesis; B: Representative hematoxylin and eosin-stained image of OA testicular tissues; C: Immunohistochemistry images for cell distribution of SPOCD1 in OA samples with normal spermatogenesis; D: Double immunostaining shows co-expression of SPOCD1 with glial cell line-derived neurotrophic factor family receptor alpha-1 (GFRA1), KIT, and proliferating cell nuclear antigen (PCNA) in testes with normal spermatogenesis; E: The abundance of SPOCD1+ cells co-expressing GFRA1, KIT, and PCNA. Each circle represents one count result, and at least 20 cross-sections of seminiferous tubules were assessed for each sample. Scale bars in B and D: 50 μm.
- Citation: Zhou D, Zhu F, Huang ZH, Zhang H, Fan LQ, Fan JY. SPOC domain-containing protein 1 regulates the proliferation and apoptosis of human spermatogonial stem cells through adenylate kinase 4. World J Stem Cells 2022; 14(12): 822-838
- URL: https://www.wjgnet.com/1948-0210/full/v14/i12/822.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v14.i12.822