Profile of biological characterizations and clinical application of corneal stem/progenitor cells

doi:10.4252/wjsc.v14.i11.777

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Nov 26, 2022 (publication date) through Dec 28, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Nov 26, 2022; 14(11): 777-797
Published online Nov 26, 2022. doi: 10.4252/wjsc.v14.i11.777

Table 4 Treatment strategies for limbal stem cell deficiency

Treatment	Description
Conservative treatment	Nonsurgical options	Autologous serum drops
		Therapeutic soft contact lens
		Therapeutic scleral lens
		Eye lubrication
	Surgical options	Corneal scraping
	Surgical options	Amniotic membrane transplantation
Invasive treatment	Conjunctival limbal autograft
	Conjunctival limbal allograft
	Keratolimbal allograft
	Ex vivo cultivated limbal epithelial stem cells
	Simple limbal epithelial transplantation
	Emerging alternative cell populations transplantation	Alternative cell populations	Oral mucosal epithelial cells
			Human embryonic stem cells
			Induced pluripotent stem cells
			Mesenchymal stem cells
			Human immature dental pulp stem cells
		Alternative cell carriers/scaffolds	Modified HAM
			Collagen
			Fibrin
			Siloxane hydrogel contact lenses
			Human lens capsule
			Poly (ε-caprolactone)
			Onion epithelial membrane scaffolds
			Carboxymethyl cellulose
			Electrospun polycaprolactone/gelatine nanocomposites

Citation: Ying PX, Fu M, Huang C, Li ZH, Mao QY, Fu S, Jia XH, Cao YC, Hong LB, Cai LY, Guo X, Liu RB, Meng FK, Yi GG. Profile of biological characterizations and clinical application of corneal stem/progenitor cells. World J Stem Cells 2022; 14(11): 777-797
URL: https://www.wjgnet.com/1948-0210/full/v14/i11/777.htm
DOI: https://dx.doi.org/10.4252/wjsc.v14.i11.777