Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes

Figure 4 Morphological and functional differences in the kidneys of streptozotocin-induced type 1 diabetes mice after mesenchymal stem cell transplantation. A: Morphological changes in the kidneys of mice were examined by hematoxylin and eosin staining. The images in the top row provide a full view of the kidneys, and the images in the bottom row are locally magnified; B and C: Mesenchymal stem cell treatment had no obvious effect on the kidney weights or kidney indexes of streptozotocin-induced type 1 diabetes mice; D-F: The serum concentrations of UREA, uric acid, and creatinine in the mice were measured. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. MSC: Mesenchymal stem cell; UcMSC: Umbilical cord-derived MSC; MenSC: Menstrual blood-derived endometrial stem cells; UA: Uric acid; CRE: Creatinine.