Review
Copyright ©The Author(s) 2021.
World J Stem Cells. Jul 26, 2021; 13(7): 841-860
Published online Jul 26, 2021. doi: 10.4252/wjsc.v13.i7.841
Figure 5
Figure 5 Pharmacological targeting of breast cancer stem cells. Insights from preclinical and clinical studies have shown that various small molecular inhibitors and antibodies against the effectors of the aberrantly expressed pathways can be targeted to downregulate the stemness and altered phenotype of breast cancer stem cells. EMT: Epithelial mesenchymal transitions; CDK: Cyclin dependent kinase; GSI: γ-secretase inhibitors; PI3K: Phosphatidylinositol 3-kinase; PTK: Protein tyrosine kinase.