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Copyright ©The Author(s) 2021.
World J Stem Cells. Jun 26, 2021; 13(6): 619-631
Published online Jun 26, 2021. doi: 10.4252/wjsc.v13.i6.619
Table 1 Molecules involved in migration and tissue homing by mesenchymal stem cells
MoleculesStage of homingRef.
Adhesion molecules CD24, CD29, CD44, CD49a-f, CD51/61VCAM-1, ICAM-1, ICAM-2, PselectinRolling, adhesion, transendothelial migrationLanger et al[55], 2009
Eseonu and De Bari[66], 2015
Chemokines receptors and chemokinesCXCR1/2/3/4/5/6, CCR1/2/4/6/8/9, MIP-1α, MCP-1, SDF-1ChemotaxisKitaori et al[67], 2009
Su et al[68], 2017
Zhang et al[73], 2015
Fu et al[74], 2019
Proinflammatory cytokines and growth factors TGF-β, IGF-1, TNF-α, IL-1β, IL-8, IL-6, IL-3, SCF, HGF, EGF, VEGF, FGF, PDGF, IGFChemotaxisDe Becker et al[70], 2007
Yuan et al[75], 2012
Gao et al[76], 2001
Extracellular matrix metalloproteinasesMMP-1, MMP-2InvasionMajumdar et al[43], 2003
Schrepfer et al[82], 2007