Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates

Figure 7 Immunohistochemical analysis of SRY-box transcription factor 2 (green) and glial fibrillary acidic protein (red) on sagittal sections of animal NPC4 spinal cord. A: Large image showing that in the site of astrogliosis SRY-box transcription factor 2 (SOX2)-positive cells predominantly localized along glial fibrillary acidic protein (GFAP)-positive processes; B and C: Three dimensional reconstruction revealed that SOX2 was not expressed by GFAP positive cells; and D: High resolution three dimensional reconstruction. Arrows show the GFAP-positive processes, surrounding SOX2-positive cells. Bar size 100 µm.