Copyright
©The Author(s) 2021.
World J Stem Cells. May 26, 2021; 13(5): 416-438
Published online May 26, 2021. doi: 10.4252/wjsc.v13.i5.416
Published online May 26, 2021. doi: 10.4252/wjsc.v13.i5.416
Ref. | LCD-Factors | LCD-domain | Nature of LCD | Experimentally confirmed | Modifications | |
In vitro | In vivo | |||||
Boija et al[46] | MED1 | C-terminus | Polar | Yes | Yes1 | NA |
Boija et al[46] Brehm et al[47] | OCT4 | N- and C-terminal domains | Acidic amino acids (electrostatic) | Yes | Yes1 | Phosphorylation |
Boija et al[46] Xue et al[48] | SOX2 | N-terminus | NA | Yes | NA | NA |
Boija et al[46] Metallo et al[49] | c-MYC | Entire polypeptide | NA | Yes | NA | NA |
Boija et al[46] Jenkins et al[50]; Oldfield et al[51] | p53 | N- and C-terminal domains | Acidic amino acids (N-terminus) | Yes | NA | Phosphorylation |
Boija et al[46] Xue et al[48] | NANOG | N- and C-terminal domains | NA | Yes | NA | NA |
Boija et al[46] | ER | NA | NA | Yes | NA | NA |
Choi et al[30] | ABCF1 | N-terminus | NA | Yes | Yes2 | NA |
Boehning et al[52] | RNA Pol II | C-terminus | Hydrophobic and electrostatic | Yes | Yes1 | Phosphorylation |
Lau et al[53] | HP1α | N-terminus | Acidic amino acids | Yes | Yes1 | Phosphorylation |
Plys et al[54] | CBX2 | Entire polypeptide | Positively charged | Yes | Yes2 | Phosphorylation |
- Citation: Vodnala M, Choi EB, Fong YW. Low complexity domains, condensates, and stem cell pluripotency. World J Stem Cells 2021; 13(5): 416-438
- URL: https://www.wjgnet.com/1948-0210/full/v13/i5/416.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v13.i5.416