Copyright
©The Author(s) 2021.
World J Stem Cells. Mar 26, 2021; 13(3): 193-207
Published online Mar 26, 2021. doi: 10.4252/wjsc.v13.i3.193
Published online Mar 26, 2021. doi: 10.4252/wjsc.v13.i3.193
Figure 1 β-cell development and maturation in vivo.
Important stages of β cell development and maturation in vivo, which mainly include distal foregut endoderm, pancreatic endoderm, endocrine progenitor, immature β cells, and mature β cells, and key transcription factors involved are described. GSIS: Glucose stimulated insulin secretion.
- Citation: Sun ZY, Yu TY, Jiang FX, Wang W. Functional maturation of immature β cells: A roadblock for stem cell therapy for type 1 diabetes. World J Stem Cells 2021; 13(3): 193-207
- URL: https://www.wjgnet.com/1948-0210/full/v13/i3/193.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v13.i3.193