Prior transfusion of umbilical cord mesenchymal stem cells can effectively alleviate symptoms of motion sickness in mice through interleukin 10 secretion

Figure 5 Western blot analysis of JAK2/ pJAK2 and STAT3/pSTAT3 expression. JAK2/STAT3 and pJAK2/pSTAT3 protein expression in the petrous part of the temporal bone was significantly upregulated in the motion sickness + mesenchymal stem cells (MS + MSCs) group compared to the MS group, and was downregulated in the MS + AS101/MSCs group on days 3 and 5 (^aP < 0.05; ^bP < 0.01; ^cP < 0.001; n = 3). A-C: JAK2/STAT3; D-F: pJAK2/pSTAT3. These experiments were performed three times with similar results. MS: Motion sickness; MSCs: Mesenchymal stem cells; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.