Age and genotype dependent erythropoietin protection in COVID-19

doi:10.4252/wjsc.v13.i10.1513

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Oct 26, 2021 (publication date) through Dec 2, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2021; 13(10): 1513-1529
Published online Oct 26, 2021. doi: 10.4252/wjsc.v13.i10.1513

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Figure 1 Age dependent erythropoietin secretion and effect of erythropoietin augmenting genetic determinants inducing ancestral neuroprotection, malaria protection, and possibly coronavirus disease 2019 protection in children. ACE: Angiotensin converting enzyme; ACE2: Angiotensin converting enzyme 2; EPO: Erythropoietin; Ang II: Angiotensin II; β-thal: Beta thalassemia; GS/BS: Gitelman syndrome/ Bartter Syndrome; HIFs: hypoxia inducible factors; SARS-COV-2: Severe acute respiratory syndrome coronavirus-2; COVID-19: Coronavirus disease 2019; RAS: Renin angiotensin system; AT1R: Ang II type 1 receptor; AT2R: Ang II type 2 receptor; eNOS: Endothelial nitric oxide synthase.

Citation: Papadopoulos KI, Sutheesophon W, Manipalviratn S, Aw TC. Age and genotype dependent erythropoietin protection in COVID-19. World J Stem Cells 2021; 13(10): 1513-1529
URL: https://www.wjgnet.com/1948-0210/full/v13/i10/1513.htm
DOI: https://dx.doi.org/10.4252/wjsc.v13.i10.1513