SOX transcription factors and glioma stem cells: Choosing between stemness and differentiation

doi:10.4252/wjsc.v13.i10.1417

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Oct 26, 2021 (publication date) through Jul 24, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2021; 13(10): 1417-1445
Published online Oct 26, 2021. doi: 10.4252/wjsc.v13.i10.1417

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Figure 5 The roles of SOX transcription factors in glioma stem cells. SOX transcription factors exert numerous functions in glioma stem cells (GSCs). They influence GSC self-renewal, stemness, tumorigenicity, sphere-forming capacity, proliferation rate, viability, migration and invasion capacities, and apoptosis. Some of the members of the SOX gene family are involved in the resistance of GSCs to therapy. Blue arrows represent stimulation, and orange bars represent inhibition. References are included in the main text. GSCs: Glioma stem cells.

Citation: Stevanovic M, Kovacevic-Grujicic N, Mojsin M, Milivojevic M, Drakulic D. SOX transcription factors and glioma stem cells: Choosing between stemness and differentiation. World J Stem Cells 2021; 13(10): 1417-1445
URL: https://www.wjgnet.com/1948-0210/full/v13/i10/1417.htm
DOI: https://dx.doi.org/10.4252/wjsc.v13.i10.1417