Mechanotransduction of stem cells for tendon repair

Figure 1 Process of mechanotransduction in stem cells for tendon repair. This figure describes various ways by which mechanical loading stimulates mechanosensors to emit mechanical signals that convert into biochemical signals, which, in turn, activate the rearrangement of cytoskeleton and activate genetic expression via various signaling pathways. Cell-cell communication transduces signals from one cell to another cell via gap junctions. GPRC: G protein-coupled receptor; GFR: Growth factor receptor.