Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review

doi:10.4252/wjsc.v12.i5.381

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. May 26, 2020; 12(5): 381-405
Published online May 26, 2020. doi: 10.4252/wjsc.v12.i5.381

Table 9 Bioluminescence imaging features for stem cell homing evaluation

Ref.	Lentiviral vector	Equipment	Software	Substrate	Dose	Image acquisition	Follow-up
Wang et al[29]	Luc2/eGFP	IVIS Lumina Series III (Perkin-Elmer)	NR	D-luciferin (Promega, United States)	100 mL (30 mg/mL)	10 min after injection	1 d, 3 d, 7 d
Yun et al[30]	Fluc/eGFP	IVIS^® Spectrum imaging system (Perkin Elmer)	NR	D-luciferin (Promega, United States)	150 mg/kg	NR	1 d, 1 wk, 3 wk
Chen et al[28]	Luc/GFP	IVIS Imaging System 200 Series (Caliper)	Living Image 3.0 (Xenogen Corp.)	D-luciferin (Caliper)	270 mg/g	15 min after injection	0, 14 d

All substrates were administered intraperitoneally. Luc: Luciferase; Fluc: Firefly luciferase; GFP: Green fluorescent protein; eGFP: Enhanced GRP; NR: Not reported.

Citation: Nucci MP, Filgueiras IS, Ferreira JM, de Oliveira FA, Nucci LP, Mamani JB, Rego GNA, Gamarra LF. Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review. World J Stem Cells 2020; 12(5): 381-405
URL: https://www.wjgnet.com/1948-0210/full/v12/i5/381.htm
DOI: https://dx.doi.org/10.4252/wjsc.v12.i5.381