Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review

Table 2 Characteristics of the studies and the stem cells used

Ref.	Yr	Country	Cell type	Source of cells	Medium culture - %FBS
Lim et al[33]	2019	South Korea	MSC	Human (adipose tissue)	DMEM - 10%FBS
Wang et al[29]	2019	China	MSC	Human (umbilical cord)	EBM-2 - 0%FBS
Yun et al[30]	2018	South Korea	NSC	Human (telencephalon)	NR
Argibay et al[38]	2017	Spain	MSC	Rat (bone marrow)	IMDM - 10%FBS
Duan et al[37]	2017	China	MSC	Rat (bone marrow)	DMEM - 10%FBS
Lu et al[35]	2017	China	NPC-Imm	Mice (C17.2)	DMEM - 10%FBS
Zhang et al[34]	2017	China	NSC	Rat (lateral ventricles)	StemPro NSC - 0%FBS
Lin et al[36]	2017	China	MSC	Rat (bone marrow)	DMEM -10%FBS
Zhang et al[39]	2016	China	NSC	Human (bone marrow)	NR
Duan et al[40]	2016	China	MSC	Rat (bone marrow)	DMEM - 10%FBS
Bai et al[42]	2015	China	MSC	Mice (bone marrow)	EBM-2
Chen et al[28]	2015	China	MSC	Human (umbilical cord)	DMEM-HG
Tan et al[41]	2015	Japan	MSC	Rat(bone marrow)	DMEM - 10%FBS,
Janowski et al[44]	2014	Poland	NSC	Human (umbilical cord)	DMEM-F12 - 2%FBS
Park et al[43]	2014	South Korea	MSC	Rat	DMEM - 0%FBS
Zhang et al[45]	2013	China	NPC-Imm	Mice (neonatal cerebellum)	DMEM - 10%FBS
Tarulli et al[46]	2013	Canada	MSC	Rat (bone marrow)	αMEM - 20%FBS
Liu et al[47]	2013	China	NSC	Rat (neonate)	DMEM-F12
Wang et al[48]	2011	China	MSC	Mice (bone marrow)	DMEM
Lee et al[50]	2009	Singapore	MSC	Human (fetal bone marrow)	DMEM - 10%FBS
Song et al[49]	2009	South Korea	NPC-Imm	Human (HB1.F3)	DMEM - 5%FBS
Kim et al[51]	2008	South Korea	MSC	Human	DMEM - 0%FBS
Guzman et al[52]	2007	United States	NSC	Human	HNCM
Syková et al[53]	2006	Czech Republic	MSC, rOEC	Mice; Human; Rat	NR
Zhu et al[54]	2005	United States	NSC	Human	NR

MSC: Mesenchymal stem cells; NSC: Neural stem cells; NPC-Imm: Neural progenitor cell - immortalised; ESC: Embryonic stem cell; rOEC: Rat olfactory ensheathing cells; C17.2: An immortalised mouse neural progenitor cell line; HB1.F3: An immortalized, clonal human NSC line; DMEM: Dulbecco's modified Eagle medium; DMEM-HG: Dulbecco's modified Eagle's medium high glucose; DMEM-F12: 50:50 mixture of DMEM and Ham's F12 medium; αMEM: Minimum essential medium Eagle: Alpha modification; EBM-2: Endothelial cell growth basal medium; IMDM: Iscove's modified Dulbecco's medium; FBS: Fetal bovine serum; StemPro NSC: Human neural stem cell culture medium; HNCN: Human neurosphere culture medium; NR: No reported.