Bone marrow-derived products: A classification proposal – bone marrow aspirate, bone marrow aspirate concentrate or hybrid?

Table 1 ACH classification

Letter	Relates to	Classification
A	BMA	1 – Collection and injection
		2 – Description of harvesting
		3 – Cell count
		4 – Dosage of cytokines (GF and/or IL)
		5 – CFU
		6 - MSC and HSC phenotyping
		7- Differentiation evaluation
		8 – Functional assays
C	BMAC	1 – Collection and injection
		2 – Description of harvesting
		3 – Cell count
		4 – Dosage of cytokines (GF and/or IL)
		5 - CFU
		6 – HSC and/or MSC phenotyping
		7 – Differentiation evaluation
		8 – Functional Assays
H	BMA + BMAC used together	1 – Collection and injection
		2 – Description of harvesting
		3 – Cell count
		4 – Dosage of cytokines (GF and/or IL)
		5 - CFU
		6 – HSC and/or MSC phenotyping
		7 – Differentiation evaluation
		8 – Functional assays

BMA: Bone marrow aspirate; BMAC: Bone marrow aspirate concentrate; CFU: colony-forming unit; MSC: Mesenchymal stem cell; HSC: Hematopoietic stem cells.