Stem cells from human exfoliated deciduous teeth ameliorate concanavalin A-induced autoimmune hepatitis by protecting hepatocytes from apoptosis

Figure 6 Schematic of treatment with stem cells from human exfoliated deciduous teeth for concanavalin A-induced hepatitis. In concanavalin A-induced acute liver injury, tumor necrosis factor-alpha and interferon-gamma activate nuclear factor-kappa B and caspase3 to induce hepatocyte apoptosis. Stem cells from human exfoliated deciduous teeth alleviate concanavalin A-induced acute liver injury via hepatocyte apoptotic inhibition, which is mediated by the nuclear factor-kappa B pathway.