Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis

Figure 2 Oxygen-glucose deprived-human neural stem cells-condition medium further promotes glioma cell proliferation and invasion. A: The proliferation of U87 and U251 MG cells was significantly increased in the condition medium (CM) groups, especially in the oxygen-glucose deprived-human neural stem cells (hNSC)-CM group, as measured by CCK8 assay; B-E: hNSC-CM promoted the invasion ability of glioma cells (U87 MG shown in B and C, U251 MG shown in D and E) compared to unconditioned hNSC medium, especially in the oxygen-glucose deprived-hNSC-CM group. Control: Unconditioned hNSC medium group. ^aP < 0.05 vs Control, ^bP < 0.01 vs Control, ^cP < 0.05 vs hNSC-CM. OGD: Oxygen-glucose deprived; hNSCs: Human neural stem cells; CM: Condition medium.