Immunophenotypic characteristics of multipotent mesenchymal stromal cells that affect the efficacy of their use in the prevention of acute graft vs host disease

Figure 4 The relative number of the different subpopulations of lymphocytes after 4 d of cultivation with multipotent mesenchymal stromal cells. A-C: Among the cultures of non-activated lymphocytes; D-F: Among the PHA-activated lymphocytes. The subpopulation fractions in the outer rings (on graphs A, B, D, E) correspond to control lymphocytes, and the internal fractions correspond to lymphocytes co-cultivated with multipotent mesenchymal stromal cells (MSCs). C and F show the relative number of lymphocytes expressing different activation markers (blue areas are lymphocyte cultures, and orange areas are lymphocyte cultures with MSCs). MSCs: Multipotent mesenchymal stromal cells.