Immunophenotypic characteristics of multipotent mesenchymal stromal cells that affect the efficacy of their use in the prevention of acute graft vs host disease

doi:10.4252/wjsc.v12.i11.1377

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Nov 26, 2020; 12(11): 1377-1395
Published online Nov 26, 2020. doi: 10.4252/wjsc.v12.i11.1377

Table 1 Characteristics of donors, CFU-F and multipotent mesenchymal stromal cells

Donor MSCs	Gender male/female	Age (median), yr	Body mass index	CFU-F per 10⁶ BM cells	Total MSC production for 4 passages, × 10⁶	Time to P0, d
No GVHD	24/17	33.19 ± 1.70 (32)	24.88 ± 0.82 (23)	17.27 ± 3.39	13.93 ± 2.14	14.44 ± 0.42
Acute GVHD	5/6	41.27 ± 4.15 (45)	26.36 ± 1.58 (27)	11.46 ± 4.50	7.71 ± 2.40	14.73 ± 0.87

MSCs: Multipotent mesenchymal stromal cells; GVHD: Graft vs host disease.

Citation: Petinati N, Kapranov N, Davydova Y, Bigildeev A, Pshenichnikova O, Karpenko D, Drize N, Kuzmina L, Parovichnikova E, Savchenko V. Immunophenotypic characteristics of multipotent mesenchymal stromal cells that affect the efficacy of their use in the prevention of acute graft vs host disease. World J Stem Cells 2020; 12(11): 1377-1395
URL: https://www.wjgnet.com/1948-0210/full/v12/i11/1377.htm
DOI: https://dx.doi.org/10.4252/wjsc.v12.i11.1377