Stem cell quiescence and its clinical relevance

Table 1 Regulation of quiescent stem cells

Stem cells	Regulatory factors
Adipose-derived stem cells	CDKI1C[14]
Airway club progenitor cells	P53[19]
Hepatic stellate cells	Laminin 521[96]
Hair follicle stem cells	MiR-22-5p[9], Acer1[43,44], Mpc1[49], OSM[83], Nlrc5[91]
Hematopoietic stem/progenitor cells	CDKI1[6], Asri[20], RB[22], Tet1[35], BMI1[36], SIN3[37], MMP[42], NRF2[45], RISP[47], SRC-3[48], Autophagy[51], NR4A1 and NR4A3[53], CD150high FOXP3+ regulatory T cells[63,71], Ebf1[64], Eosinophils[66], ICAM-1[69], lineage-committed Hdc+ myeloid cells[72], NG2+ cells[73], NPY[74], ANG[77], SHP-1[78], TGF-β[80], luteinizing hormone[89], Jak1[84], PTPN21[97]
Mammary stem cells	BCL11b[16], FOXP1
Muscle satellite (stem) cells	Rpt3[7], miR-708[27], Notch3[28,29], PTEN[30,31], ZEB1[31,55,56], miR-31[39], AMPK[46], N-cadherin and M-cadherin[68], Wnt4[75], OSM[76], Nlrc5[91], Col5a1[95]
Neural stem/progenitor cells	Notch2[8], Lfng[23], ID4[24], Notch3[25], Cpt1a[41], ASCL1[57], Huwe1[58], VCAM-1[67], MFGE8[86]