Inflammatory bowel disease: Therapeutic limitations and prospective of the stem cell therapy

doi:10.4252/wjsc.v12.i10.1050

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Oct 26, 2020 (publication date) through Nov 30, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2020; 12(10): 1050-1066
Published online Oct 26, 2020. doi: 10.4252/wjsc.v12.i10.1050

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Figure 2 The mucosal lining of the intestine is disrupted due to prolonged local inflammation and thus allowing migration of gut bacteria into intestinal tissues. Stem cells by virtue of having immune modulatory capabilities down-regulate local inflammation, and because of ability to migrate and settle in injured tissues can migrate to damaged regions of intestines, settle there and differentiate into cell types of immediate surrounding to help in mucosal healing.

Citation: Mishra R, Dhawan P, Srivastava AS, Singh AB. Inflammatory bowel disease: Therapeutic limitations and prospective of the stem cell therapy. World J Stem Cells 2020; 12(10): 1050-1066
URL: https://www.wjgnet.com/1948-0210/full/v12/i10/1050.htm
DOI: https://dx.doi.org/10.4252/wjsc.v12.i10.1050