Regeneration of the central nervous system-principles from brain regeneration in adult zebrafish

Figure 3 Established paradigms to study cellular and molecular mechanisms of regeneration in the telencephalon and cerebellum of adult zebrafish. A: Mechanical injury to lesion the adult zebrafish telencephalon, damaging the ventricular zone containing neural stem cells; B: Mechanical injury to lesion the adult zebrafish telencephalon, sparing the ventricular zone containing neural stem cells; C: Cerebroventricular microinjections of Aβ42 derivatives to study neurodegeneration in the adult zebrafish telencephalon; D: Mechanical injury of the adult zebrafish cerebellum.