Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits

doi:10.4252/wjsc.v11.i12.1115

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Dec 26, 2019; 11(12): 1115-1129
Published online Dec 26, 2019. doi: 10.4252/wjsc.v11.i12.1115

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Figure 6 Representative radiological images 8 wk after cell transplantation. A: Sham control; B: Anterior cruciate ligament transection alone; C: Low-dose (1.7 × 10⁶) hADMSCs; D: High-dose (1.7 × 10⁷) hADMSCs; E: Low-dose (1.7 × 10⁶) hADMSCs + TSP2 (100 ng); F: TSP2. Black arrowhead: Osteophytes in medial femoral condyle; White arrow: Deformity of medial tibia; White arrowhead: Sharpening of tibial spine. hADMSCs: Human adipose-derived mesenchymal stem cells; TSP2: Thrombospondin 2.

Citation: Shin K, Cha Y, Ban YH, Seo DW, Choi EK, Park D, Kang SK, Ra JC, Kim YB. Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits. World J Stem Cells 2019; 11(12): 1115-1129
URL: https://www.wjgnet.com/1948-0210/full/v11/i12/1115.htm
DOI: https://dx.doi.org/10.4252/wjsc.v11.i12.1115