Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits

doi:10.4252/wjsc.v11.i12.1115

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Dec 26, 2019; 11(12): 1115-1129
Published online Dec 26, 2019. doi: 10.4252/wjsc.v11.i12.1115

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Figure 5 Time-course radiological evaluation on knee joints. Open circle: Sham control; Filled circle: Anterior cruciate ligament transection alone; Inverted triangle: Low-dose (1.7 × 10⁶) hADMSCs; Square: High-dose (1.7 × 10⁷) hADMSCs; Lozenge: Low-dose (1.7 × 10⁶) hADMSCs + TSP2 (100 ng); Triangle: TSP2. ^aSignificantly different from sham control, P < 0.05. ^bSignificantly different from ACLT alone, P < 0.05. hADMSCs: Human adipose-derived mesenchymal stem cells; TSP2: Thrombospondin 2.

Citation: Shin K, Cha Y, Ban YH, Seo DW, Choi EK, Park D, Kang SK, Ra JC, Kim YB. Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits. World J Stem Cells 2019; 11(12): 1115-1129
URL: https://www.wjgnet.com/1948-0210/full/v11/i12/1115.htm
DOI: https://dx.doi.org/10.4252/wjsc.v11.i12.1115