Characterization of inflammatory factor-induced changes in mesenchymal stem cell exosomes and sequencing analysis of exosomal microRNAs

Table 1 Differentially expressed miRNAs

Top 10 differentially expressed miRNAs
Control group			VCAM-1 group			In the TNFα group			In the IL6 group
sRNA id	Count (16379497)	TPM	sRNA id	Count (23095609)	TPM	sRNA id	Count (20739574)	TPM	sRNA id	Count (32116232)
miR-21-5p	1544110	76933.99	miR-21-5p	1640334	70885.38	miR-21-5p	1454726	70066.87	miR-21-5p	1323387
miR-127-3p	159283	9724.54	miR-127-3p	259830	11250.19	miR-100-5p	408192	19681.79	miR-199a-3p,miR-199b-3p	317377
miR-199a-3p,miR-199b-3p	139220	8499.65	miR-199a-3p, miR-199b-3p	155376	6727.51	miR-127-3p	321306	15492.41	miR-127-3p	300549
miR-100-5p	132865	8111.67	miR-100-5p	140774	6095.27	miR-199a-3p, miR-199b-3p	271902	13110.3	miR-100-5p	265054
miR-222-3p	89564	5468.06	miR-26a-5p	107800	4667.55	miR-23a-3p	140623	6780.42	miR-34a-5p	178542
miR-26a-5p	77524	4732.99	miR-34a-5p	86786	3757.68	miR-222-3p	129932	6264.93	miR-23a-3p	144385
miR-34a-5p	76681	4681.52	miR-451a	77297	3346.83	miR-146a-5p	128078	6175.54	miR-222-3p	111957
miR-181a-5p	67287	4108	miR-23a-3p	71930	3114.44	miR-34a-5p	119952	5783.73	miR-146a-5p	100038
miR-411-5p	56606	3455.91	miR-196a-5p	63939	2768.45	miR-143-3p	101398	4889.11	miR-26a-5p	98114
miR-143-3p	49739	3036.66	miR-181a-5p	62752	2717.05	miR-26a-5p	99628	4803.76	miR-181a-5p	97685

Count is the number of mapped tags, and the value in parentheses is the total number. Transcripts per kilobase million is the standardized expression value. VCAM-1: Vascular cell adhesion molecule-1; TNF: Tumor necrosis factor; IL6: Interleukin 6; TPM: Transcripts per kilobase million.