Cytokines in adipose-derived mesenchymal stem cells promote the healing of liver disease

Figure 4 Adipose-derived mesenchymal stem cells improved symptoms of tissue fibrosis in cirrhosis caused by the administration of CCL4. Micrographic image of Azan staining of liver specimens. Azan staining is a fibrous connective tissue staining method that differentiates collagen fibers and muscle fibers. The fibrous connective tissue in the tissue section was stained blue. Microscopic images of the liver specimens 20 h after the administration of PBS (upper panels) and adipose-derived mesenchymal stem cells (ADSC) (lower panels) via the mouse tail vein. In the ADSC administration group, fibrosis and pseudolobule formation were ameliorated. Microscopic images (×100 - 400) of the same tissue section.