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©The Author(s) 2020.
世界华人消化杂志. 2020-11-28; 28(22): 1128-1136
在线出版 2020-11-28. doi: 10.11569/wcjd.v28.i22.1128
在线出版 2020-11-28. doi: 10.11569/wcjd.v28.i22.1128
表2 结直肠癌患者的总生存期与无进展生存期的单因素COX分析
OS | PFS | |||
HR (95%CI) | P值 | HR (95%CI) | P值 | |
性别 | 1.016 (0.699-1.478) | 0.932 | 1.172 ( 0.828-1.656) | 0.37 |
年龄 | 2.214 (1.449-3.381) | <0.001 | 1.068 (0.754-1.512) | 0.711 |
肿瘤位置 | 0.157 | 0.98 | ||
左半 | Ref. | Ref. | ||
右半 | 1.487 (0.986-2.241) | 0.058 | 1.033 (0.709-1.506) | 0.862 |
未知 | 1.147 (0.646-2.033) | 0.639 | 0.994 (0.607-1.626) | 0.981 |
放射治疗 | 1.340 (0.919-1.953) | 0.128 | 0.909 (0.644-1.283) | 0.59 |
HOXB8表达水平 | 1.148 (0.788-1.673) | 0.472 | 1.742 (1.222-2.482) | 0.002 |
AJCC T stage | <0.001 | <0.001 | ||
T1 | Ref. | Ref. | ||
T2 | 0.924 (0.195-4.367) | 0.92 | 0.864 (0.186-4.008) | 0.852 |
T3 | 1.769 (0.434-7.211) | 0.425 | 2.342 (0.576-9.512) | 0.233 |
T4 | 5.622 (1.326-23.842) | 0.019 | 6.738 (1.600-28.380) | 0.009 |
AJCC N stage | <0.001 | <0.001 | ||
N0 | Ref. | Ref. | ||
N1 | 1.717 (1.070-2.757) | 0.025 | 1.680 (1.099-2.569) | 0.016 |
N2 | 4.005 (2.593-6.185) | <0.001 | 4.082 (2.716-6.135) | <0.001 |
AJCC M stage | <0.001 | <0.001 | ||
M0 | Ref. | Ref. | ||
M1 | 3.904 (2.569-5.932) | <0.001 | 4.681 (3.187-6.875) | <0.001 |
Mx | 1.716 (0.921-3.197) | 0.088 | 1.207 (0.656-2.217) | 0.545 |
AJCC stage | <0.001 | <0.001 | ||
Ⅰ | Ref. | Ref. | ||
Ⅱ | 1.883 (0.784-4.519) | 0.156 | 2.241 (1.051-4.776) | 0.036 |
Ⅲ | 3.450 (1.455-8.180) | 0.004 | 3.370 (1.577-7.203) | 0.001 |
Ⅳ | 8.064 (3.390-19.183) | <0.001 | 10.66 (4.990-22.779) | <0.001 |
引文著录: 池强伟, 赵畅, 李绍堂. 基于HOXB8基因的结直肠癌预后模型及列线图的建立与验证. 世界华人消化杂志 2020; 28(22): 1128-1136