血清糖蛋白2作为预测急性胰腺炎严重程度标识物的研究

表1 患者的一般资料

病理特征	总数(n = 59)	轻度(n = 30)	中等(n = 16)	重度(n = 13)	P值
年龄(岁)	64.0 (52.5-77.0)	62.5(49.5-72.3)	66.5(53.5-77.8)	77.0(42.0-81.5)	0.571
性别(男/女)	26/33	11/19	7/9	8/5	0.324
病因					0.065
胆源性	24 (40.7%)	13 (43.3%)	7 (43.8%)	4 (30.8%)
酒精性	8 (13.6%)	1 (3.3%)	4 (25.0%)	3 (23.1%)
ERCP术后	7 (11.9%)	3 (10.0%)	2 (12.5%)	2 (15.4%)
BMI>30 kg/m2	14 (23.7%)	7 (23.3%)	3 (18.8%)	4 (30.8%)	0.749
BISAP评分	1 (1-2)	1 (0-2)	2 (1-3)	2 (1-3)	0.005
Charlson指数	0	0	1 (0-2)	1 (0-2)	0.035
CRP(mg/dL)	10.9 (3.0-24.2)	4.3(1.8-12.7)	19.8 (9.6-28.4)	30.4(23.2-39.3)	<0.001
SIRS发生率	29 (49.2%)	9 (30%)	11 (68.8%)	9 (75%)	0.007
SIRS>48 h	14 (23.7%)	0	3 (18.8%)	11 (84.6%)	<0.001
胰腺坏死	9 (15.3%)	0	3 (18.8%)	6 (46.2%)	0.001
胰周组织坏死	9 (15.3%)	0	3 (18.8%)	6 (46.2%)	<0.001
败血症	5 (8.5%)	0	0	5 (38.5%)	<0.001
器官衰竭	13 (22.0%)	0	0	13 (100%)	<0.001
住院天数	12 (7.0-18.5)	8.5 (6.0-12.3)	14 (11.0-20.0)	32.5 (3.8-52.3)	0.014
死亡率	8(13.6%)	0	0	8 (61.5%)	<0.001

BISAP: 急性胰腺炎严重程度床边指数; SIRS: 全身炎症反应综合症; CRP: C反应蛋白; ERCP: 经内镜逆行胰胆管造影; BMI: 身体质量指数.