中国宁夏人群HOTAIR单核苷酸多态性与胃癌易感性的相关性研究

表2 HOTAIR 中3个基因位点的单核苷酸多态性与胃癌的遗传易感相关性分析 n (%)

SNP	对照组(n = 307)	实验组(n = 152)	OR (95%CI)	P 值
Rs12826786
CC	213 (69.3)	86 (56.6)	1
C/T	72 (23.5)	42 (27.6)	2.017 (0.869-3.014)	0.978
TT	22 (7.2)	24 (15.8)	1.629 (0.854-4.146)	0.626
C/T OR TT	94 (30.7)	66 (43.3)	1.487 (0.394-2.121)	0.411
Rs920778
CC	135 (44.0)	80 (52.6)	1
C/T	96 (31.3)	32 (21.1)	0.942 (0.627-1.423)	0.642
TT	76 (24.7)	40 (26.3)	1.454 (1.069-1.927)	0.029
C/T OR TT	96 (21.3)	62 (21.0)	1.042 (0.727-1.493)	0.122
rs4359714
AA	242 (78.8)	108 (71.1)	1
A/G	47 (15.3)	31 (20.4)	0.766 (0.446-1.315)	0.334
GG	18 (5.9)	13 (8.5)	2.571 (0.418-15.170)	0.314
A/G OR GG	39 (8.6)	24 (9.1)	1.009 (0.592-1.720)	0.973