基于Logistic、ROC分析直肠癌放化疗导致急性骨髓抑制的物理因素分析

表2 单因素分析≥2级急性骨髓抑制的物理因素 (mean ± SD)

物理	骨盆			骶骨			髂骨			骨盆下部
因素	等级<2	等级≥2	P值	等级<2	等级≥2	P值	等级<2	等级≥2	P值	等级<2	等级≥2	P值
V5 (%)	98.24 ± 2.13	98.37 ± 2.14	0.819	98.64 ± 3.68	99.42 ± 2.11	0.355	99.28 ± 2.06	99.67 ± 1.08	0.329	97.32 ± 4.27	96.64 ± 4.71	0.572
V10 (%)	93.05 ± 4.36	92.57 ± 4.12	0.667	97.26 ± 5.56	98.22 ± 3.87	0.424	93.73 ± 4.87	94.49 ± 3.07	0.499	90.41 ± 7.63	87.48 ± 8.96	0.191
V15 (%)	88.28 ± 6.56	88.20 ± 5.15	0.966	95.73 ± 6.79	96.99 ± 5.10	0.409	87.65 ± 6.49	89.53 ± 4.30	0.177	84.84 ± 10.46	81.56 ± 10.78	0.243
V20(%)	79.76 ± 8.08	80.50 ± 6.62	0.695	93.58 ± 7.99	95.32 ± 6.40	0.349	76.44 ± 8.46	80.67 ± 7.64	0.048a	74.66 ± 13.34	71.42 ± 11.62	0.318
V25 (%)	65.50 ± 7.90	66.89 ± 6.58	0.460	89.42 ± 8.72	91.94 ± 7.83	0.242	57.37 ± 8.32	62.32 ± 9.39	0.041	58.41 ± 15.76	55.18 ± 10.41	0.335
V30 (%)	51.18 ± 8.44	52.86 ± 6.34	0.379	79.99 ± 10.20	83.80 ± 9.77	0.148	39.21 ± 7.05	45.59 ± 7.42	0.001a	44.98 ± 16.72	39.75 ± 9.41	0.121
V35 (%)	36.82 ± 7.95	38.68 ± 6.33	0.313	64.54 ± 10.99	69.51 ± 10.10	0.075	25.37 ± 7.06	30.50 ± 6.80	0.008	30.78 ± 14.81	26.51 ± 7.68	0.145
V40 (%)	25.12 ± 6.65	26.49 ± 5.49	0.382	49.19 ± 10.90	54.12 ± 9.89	0.072	14.90 ± 4.89	17.49 ± 5.08	0.054	19.95 ± 11.37	16.68 ± 5.99	0.145
V45 (%)	15.56 ± 7.40	17.62 ± 5.52	0.215	32.66 ± 14.73	39.17 ± 10.85	0.052a	8.23 ± 4.21	10.38 ± 4.21	0.056	11.84 ± 9.20	10.19 ± 4.21	0.370
V50 (%)	6.86 ± 6.36	8.72 ± 5.56	0.232	14.37 ± 14.03	20.62 ± 12.18	0.070	3.22 ± 3.10	4.70 ± 3.45	0.094	5.04 ± 6.09	4.82 ± 3.59	0.877
Dmax (CGy)	5212 ± 479	5354 ± 380	0.225	5216 ± 496	5364 ± 326	0.201	5104 ± 386	5221 ± 292	0.182	5110 ± 383	5212 ± 221	0.25
Dmean (CGy)	3050 ± 272	3104 ± 230	0.43	3835 ± 359	4002 ± 34	0.063	2778 ± 23	2927 ± 221	0.014	2782 ± 383	2702 ± 333	0.388

BMS分级<2级25例, ≥2级38例.

^aP<0.05, 比较物理因素<2级和≥2级急性骨髓抑制显示, 两者不存在多重线性.