急性胰腺炎血浆纤维蛋白相关标志物的动态变化及临床意义

表1 有无POF的AP病人的人口统计学和生化指标的比较

变量	POF组 (n = 32)	无POF组 (n = 120)	t (χ2)	P
年龄	50.28 ± 14.13	46.88 ± 14.43	-1.191	0.2351
性别 (男/女)	24/8 (75.0%)	68/52 (56.7%)	3.554	0.0592
病因
高脂血症	12/65 (18.5%)	53/65 (81.5%)	0.47	0.9252
胆源性	13/57 (22.8%)	44/57 (77.2%)
酗酒	1/4 (25.0%)	3/4 (75%)
不明原因	6/26 (23.1%)	20/26 (76.9%)
ALT (U/L)	97.39 ± 169.14	74.56 ± 127.42	0.822	0.4121
AST (U/L)	73.57 ± 92.08	67.04 ± 118.20	0.281	0.7791
总胆 (mg/dL)	29.08 ± 34.31	16.25 ± 11.81	2.05	0.0491
直胆 (mg/dL)	15.58 ± 27.91	6.04 ± 7.75	1.914	0.0651
LDH (U/L)	283.87 ± 82.20	239.43 ± 92.45	2.369	0.0191
淀粉酶 (U/L)	590.18 ± 572.56	635.85 ± 1010.81	-0.229	0.8191
血糖 (mg/dL)	11.26 ± 4.77	8.17 ± 3.99	3.714	0.0001
BUN (mg/dL)	4.70 ± 2.24	6.74 ± 12.95	-0.884	0.3781
Cr (mg/dL)	68.19 ± 27.43	61.87 ± 23.81	1.287	0.2001
白蛋白 (g/L)	39.67 ± 9.16	44.73 ± 7.60	-3.188	0.0021
钙 (mg/dL)	2.54 ± 1.54	2.29 ± 0.40	0.86	0.3971
钠 (mmol/L)	137.31 ± 5.22	138.19 ± 4.78	-0.877	0.3821
CRP (mg/L)	76.03 ± 88.97	46.70 ± 75.41	1.874	0.0631

¹t-检验,

²χ²检验. POF: 伴持续器官功能衰竭; AP: 急性胰腺炎; ALT: 谷丙转氨酶; AST: 谷草转氨酶; LDH: 乳酸脱氢酶; BUN: 血尿素氮; Cr: 肌酐; CRP: C-反应蛋白.