利用微阵列芯片技术探究基因FOXQ1与大肠癌的关系

表2 FOXQ1敲低后, 下调倍数最大的20个基因

基因名称	倍性变化	mRNA编号	描述
TCF24	-7.699125	NM_001193502	Homo sapiens transcription factor 24 (TCF24)
MORN5	-6.097624	NM_198469	Homo sapiens MORN repeat containing 5 (MORN5)
GRK1	-5.3753	NM_002929	Homo sapiens G protein-coupled receptor kinase 1 (GRK1)
SPOCD1	-4.863297	NM_144569	Homo sapiens SPOC domain containing 1 (SPOCD1)
GDF6	-4.438107	NM_001001557	Homo sapiens growth differentiation factor 6 (GDF6)
SLC39A8	-4.372665	NM_001135147	Homo sapiens solute carrier family 39 (zinc transporter), member 8 (SLC39A8)
FAM48B2	-4.206	NM_001136233	Homo sapiens family with sequence similarity 48, member B2 (FAM48B2)
SERPINI1	-3.898295	NM_005025	Homo sapiens serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1)
MYBPH	-3.67658	NM_004997	Homo sapiens myosin binding protein H (MYBPH)
VPS53	-3.553322	NM_001128159	Homo sapiens vacuolar protein sorting 53 homolog (S. cerevisiae) (VPS53)
C3	-3.442721	NM_000064	Homo sapiens complement component 3 (C3)
-	-3.427454	-	HSU45880 X-linked inhibitor of apotosis protein {Homo sapiens} (exp = -1; wgp = 0; cg = 0), partial (29%) [THC2703908]
ZNF879	-3.426777	NM_001136116	Homo sapiens zinc finger protein 879 (ZNF879)
CCL20	-3.145884	NM_004591	Homo sapiens chemokine (C-C motif) ligand 20 (CCL20)
FMR1NB	-3.13995	NM_152578	Homo sapiens fragile X mental retardation 1 neighbor (FMR1NB)
GNN	-3.113418	NR_027249	Homo sapiens Grp94 neighboring nucleotidase pseudogene (GNN), non-coding RNA [NR_027249]
LOC400568	-3.076233	BC043554	Homo sapiens cDNA clone IMAGE:5176687. [BC043554]
DGCR14	-3.033284	NM_022719	Homo sapiens DiGeorge syndrome critical region gene 14 (DGCR14)
S100A8	-2.988219	NM_002964	Homo sapiens S100 calcium binding protein A8 (S100A8)
RN28S1	-2.977916	NR_003287	Homo sapiens RNA, 28S ribosomal 1 (RN28S1), ribosomal RNA [NR_003287]