利用微阵列芯片技术探究基因FOXQ1与大肠癌的关系

表1 FOXQ1敲低后, 上调倍数最大的20个基因

基因名称	倍性变化	mRNA编号	描述
GPA33	6.626402	NM_005814	Homo sapiens glycoprotein A33 (transmembrane) (GPA33)
DNMBP-AS1	6.349088	NR_024130	Homo sapiens DNMBP antisense RNA 1 (non-protein coding) (DNMBP-AS1), non-coding RNA [NR_024130]
ANGPTL4	5.696401	NM_139314	Homo sapiens angiopoietin-like 4 (ANGPTL4)
DUOX2	5.223868	NM_014080	Homo sapiens dual oxidase 2 (DUOX2)
IL1B	4.755472	NM_000576	Homo sapiens interleukin 1, beta (IL1B)
BLNK	4.511446	NM_013314	Homo sapiens B-cell linker (BLNK)
VTCN1	4.171324	NM_024626	Homo sapiens V-set domain containing T cell activation inhibitor 1 (VTCN1)
SFTPB	4.070699	NM_000542	Homo sapiens surfactant protein B (SFTPB)
SHE	4.028845	NM_001010846	Homo sapiens Src homology 2 domain containing E (SHE)
-	3.957717	DB335107	DB335107 SYNOV4 Homo sapiens cDNA clone SYNOV4009599 3', mRNA sequence [DB335107]
LOC100131581	3.913005	AK092544	Homo sapiens cDNA FLJ35225 fis, clone PROST2001116. [AK092544]
REPS2	3.894184	NM_004726	Homo sapiens RALBP1 associated Eps domain containing 2 (REPS2)
C7orf60	3.657602	NM_152556	Homo sapiens chromosome 7 open reading frame 60 (C7orf60)
DUOXA2	3.601023	NM_207581	Homo sapiens dual oxidase maturation factor 2 (DUOXA2)
C5orf4	3.594347	NM_032385	Homo sapiens chromosome 5 open reading frame 4 (C5orf4)
LOC283050	3.530351	NR_024431	Homo sapiens uncharacterized LOC283050 (LOC283050), transcript variant 1, non-coding RNA [NR_024431]
LOC100132354	3.422083	NR_024478	Homo sapiens uncharacterized LOC100132354 (LOC100132354), non-coding RNA [NR_024478]
ITM2B	3.385245	NM_021999	Homo sapiens integral membrane protein 2B (ITM2B)
ALDOC	3.37901	NM_005165	Homo sapiens aldolase C, fructose-bisphosphate (ALDOC)
C15orf48	3.370889	NM_032413	Homo sapiens chromosome 15 open reading frame 48 (C15orf48)