以iTRAQ技术分析大鼠肝纤维化发展成肝癌过程中肝组织差异表达的蛋白质

表1 大鼠肝纤维化发展成肝癌过程中肝组织表达上调的蛋白

Accession	Protein Description	Ratio
		113:117	114:117	115:117	116:117
tr|G3V786	Protein Akr1b8	2.773	4.983	4.739	3.730
sp|P24329	Thiosulfate sulfurtransferase	1.584	2.554	1.538	3.647
sp|P07335	Creatine kinase B-type	2.33	2.835	1.907	3.435
sp|B1H267	Sorting nexin-5	3.564	4.846	3.727	3.193
sp|P38983	40S ribosomal protein SA	2.569	2.521	1.409	3.135
tr|Q6P7Q6	Galectin	1.842	1.503	1.642	2.819
sp|Q4G061	Eukaryotic translation initiation factor	2.328	4.656	2.689	2.813
tr|Q6I8Q6	Histone H2A	2.609	1.336	1.343	2.784
sp|Q5FVQ4	Malectin	1.822	1.503	1.642	2.819
sp|Q4KM35	Proteasome subunit beta type-10	1.975	2.163	1.532	2.437
tr|D4AAV1	Protein Amdhd1	2.337	2.217	1.896	2.423
sp|P45479	Palmitoyl-protein thioesterase 1	2.649	2.383	1.288	2.419
sp|P97584	Prostaglandin reductase 1	1.691	2.433	2.593	2.341
sp|O35796	Complement component 1 Q	1.222	1.334	1.274	2.315
sp|B0BN18	Prefoldin subunit 2	2.569	1.296	2.172	2.043
sp|P80067	Dipeptidyl peptidase 1	1.908	1.423	1.614	2.009
tr|Q6AY21	GTPase activating protein (SH3 domain) binding protein 2	2.064	2.519	1.280	1.934
tr|F1LM19	Alpha-2-HS-glycoprotein	1.963	1.283	1.274	1.903
sp|Q920L2	Succinate dehydrogenase [ubiquinone] flavoprotein subunit	1.571	1.443	1.594	1.722
sp|P35704	Peroxiredoxin-2	1.395	1.561	1.679	1.701
sp|Q5M827	Pirin	2.095	2.816	2.061	1.701
sp|Q63716	Peroxiredoxin-1	1.606	1.827	1.762	1.689
sp|Q62812	Myosin-9	1.252	1.222	1.894	1.681
sp|Q10758	Keratin, type II cytoskeletal 8	1.394	1.339	1.334	1.646
tr|G3V9E3	Caldesmon 1	2.335	1.589	1.630	1.636
sp|Q9ER34	Aconitate hydratase	1.351	1.365	1.369	1.565
sp|P32755	4-hydroxyphenylpyruvate dioxygenase	1.26	1.482	1.205	1.527
sp|Q8CFN2	Cell division control protein 42 homolog	1.483	1.570	1.329	1.504
tr|M0RBJ7	Complement C3	1.292	1.268	1.789	1.472
sp|Q99MC0	Protein phosphatase 1 regulatory subunit 14A	1.775	1.653	1.945	1.467
sp|Q9Z0U5	Aldehyde oxidase 1	1.605	1.859	2.322	1.399
tr|F1LP60	Moesin	1.378	1.201	1.281	1.383
sp|P09811	Glycogen phosphorylase	2.818	4.695	1.802	1.322
sp|P17220	Proteasome subunit alpha type-2	1.521	1.557	1.332	1.282
sp|P28064	Proteasome subunit beta type-8	1.256	1.381	1.399	1.259
sp|P46413	Glutathione synthetase	1.253	1.306	1.224	1.214
tr|F1LNY0	Uncharacterized protein	1.316	1.376	1.439	1.194