自身免疫性肝炎患者血清学指标与肝活检病理的关系

表2 血清学指标与肝脏纤维化分期的结果比较

分期	n	ALT(U/L)	AST(U/L)	γ-GT(U/L)	ALP(U/L)	IBIL(μmol/L)	TP(g/L)	ALB(g/L)	GLB(g/L)	A/G	TBIL(μmol/L)	DBIL(μmol/L)	PT(s)	PTA(%)	APTT(s)	FIB(g/L)
S0	42	66.0 (9.0-1585.0)	63.0 (16.0-474.0)	74.0 (8.0-670.0)	103.0 (44.0-903.0)	9.0 (1.9-119.5)	74.6 (59.1-85.9)	41.3 (30.9-47.5)	30.1 (23.4-45.6)	1.31± 0.33	13.0 (4.7-390.4)	4.3 (2.2-270.9)	12.6 (11.1-14.8)	94.7 (76.0-150.0)	37.2 (22.5-41.2)	2.8 (1.4-6.1)
S1	50	91.0 (6.0-806.0)	84.0 (20.0-1317.0)	113.0 (10.0-771.0)	112.0 (58.0-616.0)	11.0 (2.1-33)	72.7 (60.6-90.7)	38.1 (29.3-41.7)	36.3 (26.2-51.9)a	1.00± 0.19a	17.1 (4.0-233.4)	6.9 (1.9-217.7)	13.3 (10.1-17.7)	94.0 (60.0-150.0)	37.2 (25.5-58.5)	2.7 (1.5-5.5)
S2	20	90.5 (8.0-215.0)	101.5 (17.0-298.0)	115.5 (19.0-290.0)	120.5 (45.0-175.0)ab	7.0 (2.5-35)	78.5 (56.9-95.2)ac	37.6 (23.1-45.6)ac	40.1 (25.8-56.5)a	0.94± 0.24a	12.3 (6.8-193.3)	6.0 (1.2-108.8)ac	13.3 (11.9-16.0)ac	87.5 (69.0-123.0)	43.5 (26.5-48.3)ac	2.2 (2.0-4.6)
S3	16	103.0 (25.0-1051.0)	87.5 (32.0-600.0)	104.0 (35.0-297.0)	169.5 (61.0-344.0)ab	16.0 (5.0-39.4)	76.2 (72.9-106.1)ac	37.4 (26.8-51.4)ac	38.0 (29.4-70.4)a	0.96± 0.42a	26.5 (9.0-120.9)	10.3 (2.2-81.5)ac	14.1 (12.0-17.5)ac	86.5 (57.0-124.0)	41.2 (33.6-52.2)ac	2.8 (1.3-3.7)
S4	18	66.0 (26.0-283.0)	84.0 (33.0-361.0)	138.0 (60.0-911.0)	205.0 (72.0-336.0)ab	9.0 (2.7-37.0)	78.5 (61.6-110.4)ac	34.5 (24.4-41.6)ac	43.3 (32.9-82.4)ac	0.77± 0.24ac	16.9 (6.3-173.8)	6.4 (2.9-137)ac	13.8 (11.7-20.1)ac	94.0 (48.0-129.0)	41.7 (34.7-59.1)ac	3.2 (1.4-4.8)
F值		1.04	2.352	2.349	-	-	-	-	8.518	13.105	-	-	5.375	1.536	-	-
P值		0.389	0.057	0.065	0.009	0.376	0.029	0	0	0	0.112	0.016	0.001	0.195	0	0.653

^aP<0.05 vs S0组;

^cP<0.05 vs S1组. 行非参数分析时无F值以-表示. ALT: 血清谷丙转氨酶; AST: 谷草转氨酶; γ-GT: 谷氨酰转肽酶; ALP: 碱性磷酸酶; IBIL: 间接胆红素; TP: 总蛋白; ALB: 白蛋白; GLB: 球蛋白; A/G: 白蛋白/球蛋白; TBIL: 总胆红素; 血清总胆红素; DBIL: 直接胆红素; PT: 凝血酶原时间; PTA: 凝血酶原活动度; APTT: 部分凝血活酶时间; FIB: 纤维蛋白原.