下调缺氧诱导因子-1α表达对肝癌细胞增殖和凋亡的影响

表4 miRNA转染HepG2细胞周期时相的影响 (%)

分组		空白	阴性	miRNA	阿霉素	阿霉素+miRNA
48 h	G0/G1	37.91±2.05	40.12±1.64a	54.78±1.64a	57.48±0.71a	60.32±1.20ade
	S	46.48±2.44	43.75±2.10a	28.43±0.76a	27.31±1.32a	24.24±1.88ace
	G2/M	15.61±0.72	16.13±0.68	16.79±1.93	15.21±0.77	15.44±1.13
72 h	G0/G1	56.75±1.13	57.43±1.27a	61.49±1.12a	61.95±0.42a	65.68±0.91adf
	S	26.14±0.78	25.56±1.21a	22.40±0.58a	21.62±1.19a	19.47±1.34ace
	G2/M	17.11±0.36	17.01±0.26	16.11±1.41	16.43±1.61	14.85±2.07

^aP<0.05 vs 空白组, G₀/G₁期q_{48 h} = 4.47, q_{72 h} = 5.50;

^dP<0.01 vs miRNA组, S期q_{48 h} = 3.51, q_{72 h} = 3.48,

^cP<0.05 vs miRNA组, G₀/G₁期q_{48 h} = 3.54,

^eP<0.05, q_{72 h} = 4.50;

^fP<0.01, S期q_{48 h} = 2.24, q_{72 h} = 2.48; ^eP<0.05 vs 阿霉素组.