戊己丸不同配伍方对炎症后肠易激综合征模型大鼠结肠运动及5-羟色胺含量的影响

表3 各组大鼠脑组织中5-HT及5-HT变化率 (mean±SD)

分组	海马			下丘脑			额叶
	5-HIAA(ng/g)	5-HT(ng/g)	5-HT转化率(%)	5-HIAA(ng/g)	5-HT(ng/g)	5-HT转化率(%)	5-HIAA(ng/g)	5-HT(ng/g)	5-HT转化率(%)
NC	265.61±21.06	280.26±35.12	95.86±13.21	668.40±63.73	369.85±47.23	182.30±20.22	258.36±40.93	280.75±51.85	95.40±26.32
M	343.54±47.84b	124.42±18.52b	281.92±63.84a	504.13±42.56a	198.58±31.63b	262.01±65.67b	425.46±64.07b	166.71±58.64b	268.36±51.49b
PC	269.28±55.66d	166.79±35.16bc	162.15±11.57bd	603.88±61.90	317.04±53.39d	195.58±40.71d	305.61±61.69d	196.06±26.39a	157.06±29.44c
W1-L	351.97±40.28bf	162.88±38.69b	222.43±37.16bd	609.75±89.58	258.45±42.08b	239.09±39.68a	339.95±87.57ac	191.17±87.03b	197.94±79.39
W1-M	317.80±23.94ae	243.16±47.50df	134.69±27.04c	627.28±59.18c	303.51±48.23ad	209.43±26.22c	279.14±25.39d	260.87±37.20de	109.36±21.84d
W1-H	283.38±40.74d	295.03±41.44df	98.61±24.65de	722.69±101.10	397.30±64.64de	184.55±28.95d	261.06±42.49d	302.75±46.36df	86.52±9.26de
W2-L	320.74±39.90ae	180.53±16.59bd	178.36±23.18b	642.89±94.54	313.24±74.53d	212.88 ±50.90c	349.61±56.55ac	212.28±40.97a	167.50±27.51a
W2-M	321.93±32.34ae	250.28±40.96df	130.57±18.72c	633.87±39.04d	339.94±55.15d	189.56±24.12d	293.05±62.28d	254.65±45.98d	115.41±16.69d
W2-H	287.92±31.24c	303.61±36.11df	95.87±15.77cf	659.40±124.99	353.02±37.48d	186.76±27.42d	261.75±62.19d	298.92±70.55df	88.47±17.76de

^aP<0.05,

^bP<0.01 vs NC组;

^cP<0.05,

^dP<0.01 vs M组;

^eP<0.05,

^fP<0.01 vs PC组. NC: 正常组; M: 模型组; PC: 阳性对照组; W1-H: 戊己丸1^#方高剂量组; W1-M: 戊己丸1^#方中剂量组; W1-L: 戊己丸1^#方低剂量组; W2-H: 戊己丸2^#方高剂量组; W2-M: 戊己丸2^#方中剂量组; W2-L: 戊己丸2^#方低剂量组. 5-HT: 5-羟色胺.