戊己丸不同配伍方对炎症后肠易激综合征模型大鼠结肠运动及5-羟色胺含量的影响

表2 各组大鼠血清和结肠中5-HT及5-HT变化率 (mean±SD)

分组	血清			结肠
	5-HIAA(ng/mL)	5-HT(ng/mL)	5-HT转化率(%)	5-HIAA(ng/g)	5-HT(ng/g)	5-HT转化率(%)
NC	82.67±4.44	2071.75±213.14	4.04±0.61	750.30±133.38	2174.38±317.92	35.07±8.11
M	65.74±12.41a	3222.28±690.29	2.09±0.39b	1005.58±112.25b	4168.36±635.80b	24.51±4.19
PC	80.16±15.06c	2402.49±826.90	3.61±1.12d	850.99±119.97c	3088.26±497.42bd	27.83±3.47
W1-L	76.43±8.52	2453.03±469.78	3.20±0.69c	890.35±150.21	3493.38±1064.29bc	26.26±3.60
W1-M	85.77±7.73d	1975.92±506.98	4.60±1.33d	798.26±120.25d	2640.41±459.79d	30.64±4.28
W1-H	92.37±7.93d	1428.82±316.46c	6.61±0.82bdf	734.58±152.88d	2086.08±442.61df	36.29±9.07
W2-L	68.27±11.20a	2413.46±451.00	2.86±0.42a	855.49±131.42	3255.63±527.84bd	26.53±3.96
W2-M	74.96±15.16	2284.58±584.61	3.40±0.73c	758.02±120.23d	2688.69±227.17d	28.36±5.05
W2-H	78.56±17.09	2001.02±278.54	4.05±1.37d	713.29±122.04d	2129.13±248.64df	33.93±7.63

^aP<0.05,

^bP<0.01 vs NC组;

^cP<0.05,

^dP<0.01 vs M组;

^fP<0.01 vs PC组. NC: 正常组; M: 模型组; PC: 阳性对照组; W1-H: 戊己丸1^#方高剂量组; W1-M: 戊己丸1^#方中剂量组; W1-L: 戊己丸1^#方低剂量组; W2-H: 戊己丸2^#方高剂量组; W2-M: 戊己丸2^#方中剂量组; W2-L: 戊己丸2^#方低剂量组. 5-HT: 5-羟色胺.